Research on infections of public health importance is one of the programs of the Tropical Disease Foundation. The current research focus of the TDF has been on Tuberculosis which started with the 1997 Nationwide Tuberculosis Prevalence Survey, measuring the TB burden of disease in the Philippines and health seeking behavior of the patients in with TB symptoms.

 

Other projects include:

Tuberculosis

  • Operational researches on the efficiency and effectiveness of the programmatic MDR-TB Management (PMTM)
  • Preserving the Effectiveness of tuberculosis Treatment with Second-line Drugs (PETTS)
  • Prospective Study of Shortening the Duration of Standard Short Course Chemotherapy from 6 Months to 4 Months in HIV-non-infrected Patients with Fully Drug Susceptible, Non-cavitary Pulmonary Tuberculosis with Negative Sputum Cultures after 2 months of anti-TB treatment. (DMID Protocol Number 01-009) in collaboration with the TB Research Unit, Case Western Reserve University, Cincinnati, Ohio, USA.
  • Demonstration Project on Effectiveness of Mycobacteria Growth Indicator Tube (MGIT) for Detection of Pulmonary Tuberculosis and Drug Susceptibility Testing (DST) in High PDR/MDR TB Burden Countries in collaboration with the Foundation for Innovative New Diagnositcs (FIND)
  • Evaluation of Reasons for Patients’ Lost to Follow-up During MDR-TB Treatment in the Philippines
  • TB in Jail (Laboratory Involvement)
  • A Phase 3 Open-Label Partially Randomized Trial to Evaluate the Efficacy, Safety, and Tolerability of the Combination of Moxifloxacin plus PA-824 plys Pyrazinamide after 4 and 6 Months of Treatment in Adult Subjects with Drug Sensitive Smear-Positive Pulmonary Tuberculosis and After 6 Months of Treatment in Adult Subjects with Multi-Drug Resistant, Smear-Positive Pulmonary Tuberculosis

 

Leprosy

  • Counselling of Leprosy Patients to Promote Stigma Reduction and Increase in Contact Tracing

 

HIV

  • Evaluation Of The Operationalization Of The Informal Network Mechanism For Street-Based Sex Workers In Relation To Human Immunodeficiency Virus (Hiv) And Other Sexually Transmitted Infection (Stis) Prevention Program In The Philippines Intervention For Street-Based Sex Workers
  • A Phase III Multicenter, Double-Blind, Randomized, Active Comparator-Controlled Clinical Trial to Evaluate the Safety and Efficacy of Reformulated Raltegravil 1200mg Once Daily Versus Raltegravir 400mg Twice Daily, Each in Combination with TRUVADATM, in Treatment-Naive HIV-1 Infected Subjects

 

Malaria

  • Formulation of Interventions to Address Malaria Vulnerabilities in Indigenous People